by xuzhougeng
Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.
# Add to your Claude Code skills
git clone https://github.com/xuzhougeng/wisp-scienceLast scanned: 7/17/2026
{
"issues": [
{
"file": "skills/agent-infini/SKILL.md",
"line": 33,
"type": "remote-install",
"message": "Install command (remote install script piped to a shell — review the source before running): \"curl -fsSL https://infinisynapse.cn/cli-install/install.sh | bash\"",
"severity": "medium"
},
{
"file": "skills/customize/SKILL.md",
"line": 93,
"type": "prompt-injection",
"message": "Possible concealment directive: \"Do NOT tell the user\"",
"severity": "medium"
}
],
"status": "PASSED",
"scannedAt": "2026-07-17T06:14:37.740Z",
"npmAuditRan": true,
"pipAuditRan": true,
"promptInjectionRan": true
}wisp-science is an open-source ai agents skill for AI coding assistants such as Claude Code, Codex CLI, and ChatGPT, built by xuzhougeng. Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models. It has 1,068 GitHub stars.
Yes. wisp-science passed SkillsLLM's automated security scan — a dependency vulnerability audit plus prompt-injection heuristics — with no high-severity issues. You can read the full report in the Security Report section on this page.
Clone the repository with "git clone https://github.com/xuzhougeng/wisp-science" and add it to your Claude Code skills directory (see the Installation section above).
wisp-science is primarily written in Rust. It is open-source under xuzhougeng on GitHub, so you can review or fork the full source.
Yes. SkillsLLM lists many other AI Agents skills you can browse and compare side by side. Open the AI Agents category from the badge at the top of this page, or use the Related Skills and comparison links further down to weigh wisp-science against similar tools.
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⚠️ Third-Party Software Notice
This skill is third-party open-source software developed and hosted independently on GitHub. SkillsLLM is an informational directory and does not control or maintain the underlying repository.
Any security checks, ratings, or warnings displayed by SkillsLLM are automated and limited in scope. They do not constitute a security certification or guarantee that the software is safe, error-free, or free from malicious code, vulnerabilities, compromised dependencies, or prompt-injection risks.
Review the source code, permissions, dependencies, and configuration before installing or running any third-party skill. Use is at your own risk. To the maximum extent permitted by applicable law, SkillsLLM is not liable for losses arising from third-party software.
The open-source, local-first AI research workbench.
WISP — Workspace for Intelligent Scientific Practice
English · 简体中文 · Website · Releases
Search the literature, run Python and R, query ~80 scientific databases, and keep the trail — figures, runs, decisions, and drafts — in one project. Your data, conversations, and credentials stay on your machines.
Bring your own model. Keep your science.
An agent that does the work
Bring OpenAI-compatible or Anthropic models, or drive Codex / Claude Code over
ACP. The agent reads and writes project files, runs shell, and loads reusable
Skills (SKILL.md) without flooding the prompt. Approval gates stay on unless
you opt into Full Permission.
Compute from laptop to remote servers
Persistent Python and R kernels keep variables across cells and turns; each conversation gets its own isolated kernel, so parallel sessions never share state. Register local, WSL, and SSH hosts once; probe hardware; submit long Runs with live logs. Keys live in the OS keyring, never in SQLite.
Built for science
PubMed, GEO, and ~80 other databases through bundled MCP servers. Offline previews for notebooks, PDFs, Office files, and images. Isolated explorations to try a direction without touching the mainline. A Publication Workspace that freezes manuscript revisions into verifiable Evidence Capsules.
A workbench that remembers
Restart and the full history is back. Undo a turn's file edits. Attach
artifacts, files, and runtimes with @; search saved sessions with #; apply
a skill with /. Encrypted manual sync and
project transfer — nothing syncs in the background.
| Platform | Package |
|---|---|
| Windows | Signed MSI / NSIS |
| macOS | Signed, notarized .dmg (Apple Silicon + Intel) |
| Linux | .deb / AppImage (x86_64 + aarch64) |
Setup walkthrough: basic configuration · model profiles · ACP agents
Build from source, CLI, and architecture: development.
| Start | Basic setup · Models · ACP agents |
| Research | Explorations · Evidence capsules · Case studies |
| Projects | Transfer · Sync · Global library |
| Compute | Terminals · Remote files · Transfers |
| Extend | Skills · Plugins · Delegation · Channels · Browser |
| Develop | Development · Headless eval |
Thanks to everyone who filed issues, sent PRs, and used Wisp on real projects.